Targeting the chemokine receptor CXCR4 for cancer therapies
May 1, 2025 · The C-X-C chemokine receptor type 4 (CXCR4) has emerged as a key molecular biomarker for cancer therapies due to its critical role in tumor progression and metastases by …
NLRP4 unlocks an NK/macrophages-centered ecosystem to …
Mar 14, 2025 · Research Open access Published: 14 March 2025 NLRP4 unlocks an NK/macrophages-centered ecosystem to suppress non-small cell lung cancer Zhouwenli …
Proteomics in pancreatic cancer - Biomarker Research
Jul 6, 2025 · While CA19-9 remains the cornerstone biomarker for these purposes, several emerging protein biomarkers are enhancing clinical applications. For example, cytokeratin 19 …
MACC1 revisited – an in-depth review of a master of metastasis
Nov 23, 2024 · Since its discovery, the value of MACC1 as a prognostic biomarker has been confirmed in over 20 cancer entities. Additionally, several therapeutic strategies targeting …
Copper homeostasis and copper-induced cell death in tumor …
Oct 31, 2024 · Cai Y, He Q, Liu W, Liang Q, Peng B, Li J, et al. Comprehensive analysis of the potential cuproptosis-related biomarker LIAS that regulates prognosis and immunotherapy of …
Novel immunotargets in multiple myeloma: biological relevance …
Jul 1, 2025 · This soluble form may act as a decoy, potentially reducing the efficacy of DPP4-targeted therapies. On the other hand, circulating soluble DPP4 has been studied as a …
Decoding tumor angiogenesis: pathways, mechanisms, and future ...
Apr 18, 2025 · Review Open access Published: 18 April 2025 Decoding tumor angiogenesis: pathways, mechanisms, and future directions in anti-cancer strategies Xueru Liu, Juan Zhang, …
Metabolic regulation of tumor-associated macrophage …
Jan 7, 2024 · Review Open access Published: 07 January 2024 Metabolic regulation of tumor-associated macrophage heterogeneity: insights into the tumor microenvironment and …